Optical coherence tomography pressure10/28/2023 ![]() Owing to the retrospective design of the study and the use of deidentified patient information, the review board waived the need for written informed consent.Īll patients underwent a standard test for cataract surgery according to the SNUH preoperative cataract examination protocol. All procedures were conducted following the tenets of the Declaration of Helsinki, and the study design was approved by the Institutional Review Board of SNUH (IRB No. This retrospective study comprised patients with cataracts from Seoul National University Hospital (SNUH), Seoul, Republic of Korea, in April 2020. This study aimed to assess the agreement between three devices, ANTERION, CASIA2, and IOLMaster 700, in terms of ocular biometry. However, so far, no previous studies have compared ANTERION and CASIA2 or all three devices in patients with cataract. They generally showed good repeatability and agreement with the IOLMaster 700 device. In addition, ANTERION with its deeper scan range, provides measurement of AL. They both provide ocular biometric measurements, including the anterior chamber depth (ACD), lens thickness (LT), and corneal keratometry. CASIA2 has a scan range of 13 mm depth and 16 mm width. CASIA2, an advanced version of CASIA SS-1000, uses a 1310 nm wavelength light with a scan speed of 50,000 A scans per second. It uses OCT-based structural images to generate ocular biometric measurements. It provides a scan depth range of 32 mm for the axial length and an in-tissue axial resolution of < 10 μm. ANTERION uses a 1300 nm central wavelength of light. ĪNTERION (Heidelberg Engineering) and CASIA2 (Tomey) are newly developed SS-OCT devices. Many studies have shown that IOLMaster 700 had good agreement with other devices, including IOLMaster 500. IOLMaster 700 (Carl Zeiss Meditec), the first SS-OCT-based biometric device, is one of the most widely used devices for cataract surgery. They are known to have a superior ability to successfully measure the axial length (AL) compared with a partial coherence interferometry device. They can provide a whole image from the cornea to the posterior lens. SS-OCT devices use 1000–1350 nm of wavelength. Recently, ocular biometry measurement devices with principles of swept-source optical coherence tomography (SS-OCT) were developed. In this regard, precise measurement of ocular biometry is critical for determining the power of IOLs. The higher the generation of the intraocular lens (IOL) calculation formula, the higher the accuracy, and more ocular biometric parameters are required. In modern cataract surgery, it is important not only to remove the cataract but also to achieve accurate postoperative refractive error. The AL of ANTERION and IOLMaster 700 showed excellent agreement. The new SS-OCT-based devices, ANTERION, and CASIA2 showed a good agreement with IOLMaster 700 in measuring ocular biometry except for the total keratometry. The CCT, ACD, and LT also showed excellent agreement (ICC > 0.9). The ANTERION and IOLMaster 700 did not obtain AL in six (12.8%) and three (6.4%) cases, respectively ( P = 0.001 by Fisher’s exact test). The AL measured by ANTERION and IOLMaster 700 showed excellent agreement (ICC = 0.999), and the mean difference was 0.005 mm. However, the ICC of the total average keratometry ranged from 0.808 to 0.952, and the difference was more than 0.43 D. Average anterior keratometry showed excellent agreement (ICC ≥ 0.989), and the mean difference was less than 0.1 D. ResultsĪ total of 47 eyes of 29 patients were measured with three devices. To assess the agreement between the devices, intraclass coefficient (ICC) and Bland-Altman analysis with 95% limits of agreement (LoA) were used. Anterior keratometry, total keratometry, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), and axial length (AL) were the main parameters for the comparison. This retrospective comparative study includes patients with cataract who underwent ocular biometric measurements with three devices, ANTERION, CASIA2, and IOLMaster 700, at Seoul National University Hospital, in April 2020. This study aimed to assess agreement between three devices. Newly developed swept-source optical coherence tomography (SS-OCT) - based ocular biometric devices, ANTERION and CASIA2 provide ocular biometric measurements as IOLMaster 700. Precise measurement of ocular biometry is critical for determining intraocular lens power.
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